This was Barnsley's 20th league defeat of the season, two more than they encountered in the whole of 2016-2017.
They have lost at least 20 games in five of the last 11 seasons.
Barnsley have now won only one of their past 11 trips to Portman Road, losing seven.
Home and away Barnsley have alos now failed to beat Ipswich in 11 meetings (D4 L7)
Prior to this match Ipswich had only scored two goals in their previous six matches.
Barnsley have failed to keep a clean sheet in any of their past 17 meetings with Ipswich.
In the Championship Barnsley have now gone eight matches without a clean sheet
This match proved to be the last for Barnsley born Mick McCarthy who resigned immedatiely after - this was his 105th win in 279 games in charge.
He is now unbeaten in seven home league matches against his home town team, last suffering defeat on his own patch against them whilst in charge of Millwall in September 1995.
Barnsley have won only four of their 14 matches played on a Tuesday this season (all comps), however this accounts for 40% of their victories this season (4/10)
Barnsley had 19 shots in the game but only two of which were on target
There were 30 fouls in total in the game - 15 by each team - the most in a Barnsley game this season. Indeed it was the most in almost exactly a year (34 at Wigan on the 13th April 2017)
Barnsley have won only one of their last eight away matches, losing six.
Ryan Hedges (for Isgrove 56)
Tom Bradshaw (for Hammill 63)
Stevie Mallan (for Fryers 82)
Jack Walton, Ethan Pinnock, Jason McCarthy, Connor Mahoney.
Bartosz Bialkowski, Cameron Carter-Vickers, Myles Kenlock, Jonas Knudsen, Jordan Spence, Callum Connolly, Barry Cotter, Mustapha Carayol, Bersant Celina, Cole Skuse, Martyn Waghorn.
Grant Ward (for Cotter 56)
Ben Folami (for Carayol 60)
Michael Crowe, Stephen Gleeson, Luke Hyam, Tristan Nydam, Freddie Sears.
Ipswich manager Mick McCarthy said:
"You can probably see why I am going. The reaction after I took Barry Cotter off - that's just pathetic," he said. "I've signed him and played him. He's absolutely knackered and has to come off.
"That was a disgraceful reaction, but I won't have to listen to it again because that's my last game - I'm out of here. It's sad because I've loved my time here.
"I can't think of one member of staff who wants me to leave or one player who wants me to leave. It's an unusual situation, isn't it? I take pride in that. I love the bones of the lads."
Sky Bet Championship results:
Tuesday 10th April 2018:
Aston Villa 1-0 Cardiff City
Bristol City 3-1 Birmingham City
Pack 12 Jutkiewicz 34
Burton Albion 0-5 Hull City
Wilson 5, Grosicki 33, 85, Meyler pen 63, Keane 90+3
Fulham 1-0 Reading
Ipswich Town 1-0 BARNSLEY
Nottingham Forest 0-1 Brentford
Preston North End 3-1 Leeds United
Gallagher pen 49 Roofe 13
Queens Park Rangers 4-2 Sheffield Wednesday
Smyth 8 Forestieri 61, Nuhiu 69
Sylla 15, pen 53
Sheffield United 2-1 Middlesbrough
Evans 2, 40 Ayala 48
Sunderland 1-1 Norwich City
Honeyman 63 Pinto 89
Bolton Wanderers 0-2 Millwall
Elliott 34, Marshall 63
Wednesday 11th April 2018:
Wolverhampton Wanderers 2-0 Derby County
Barnsley lie in 22nd place in the Sky Bet Championship with 37 points from 41 games.
We are 31 points outside the Play-Offs, 44 points off the Automatic Promotion Places, 55 points off First place and 2 points inside the Relegation Zone.
Up to 11/04/18
Sky Bet Championship Matchday Thirty Forty Two: Barnsley v Bolton Wanderers, Saturday 14th April 2018. Kick-Off: 3pm
On The Road:
Sky Bet Championship Matchday Thirty Forty Three: Leeds United v Barnsley, Saturday 21st April 2018. Kick-Off: 3pm